4-Fluorobenzaldehyde #CAS459-57-4
4-Fluorobenzaldehyde #CAS459-57-4
p-Fluorobenzaldehyde (4-fluorobenzaldehyde) is a very important fine chemical with significant applications in pharmaceuticals, pesticides, new materials, and polymers. For example, in the pharmaceutical field, it is a key raw material used to manufacture the core of rosuvastatin calcium, making it extremely valuable, as it is crucial for important drugs such as haloperidol, fluperazole, and rosuvastatin calcium.
Application of 4-Fluorobenzaldehyde
4-Fluorobenzaldehyde is a fluorinated benzaldehyde with inhibitory activity of mushroom tyrosinase. 4-Fluorobenzaldehyde is commonly used as a synthetic intermediate in the preparation of pharmaceutic al compounds.
Usually used in the preparation of pyrazolopyridine UR-13756.
4-Fluorobenzaldehyde is used in the preparation of pyrazolopyridine derivative, which finds application as mitogen-activated protein kinase (MAPK) inhibitor. It also serves as a synthetic intermediate in the preparation of pharmaceutical compounds.
| 4-Fluorobenzaldehyde Chemical Properties |
| Melting point | -10 °C (lit.) |
| Boiling point | 181 °C/758 mmHg (lit.) |
| density | 1.157 g/mL at 25 °C (lit.) |
| vapor pressure | 19 hPa (70 °C) |
| refractive index | n |
| Fp | 134 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform, Methanol |
| form | Liquid |
| color | Clear colorless to yellow |
| Specific Gravity | 1.157 |
| Water Solubility | IMMISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 385857 |
| Stability: | Air Sensitive |
| InChI | 1S/C7H5FO/c8-7-3-1-6(5-9)2-4-7/h1-5H |
| InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
| SMILES | [H]C(=O)c1ccc(F)cc1 |
| CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
| EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
| Safety Information |
| Hazard Codes | Xi,F |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-37/39-36/37/39-27 |
| RIDADR | UN 1989 3/PG 3 |
| WGK Germany | 2 |
| F | 9-23 |
| Hazard Note | Flammable |
| TSCA | TSCA listed |
| HazardClass | 3.2 |
| PackingGroup | III |
| HS Code | 29130000 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 2 Eye Irrit. 2 Flam. Liq. 3 |
Fact Factory and Equipment Show
