Potassium tert-butoxide #CAS865-47-4
CAS Number：865-47-4
Synonyms:
PotassiuM tert-butoxide reagent grade, >=98%
Potassium-2-methylpropan-2-olate solution
Potassium tert-butylate 1M in THF
Appearance: White To Off-white Solution
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Potassium tert-butoxide #CAS865-47-4
Potassium tert-butoxide is an important kind of organic base with its alkalinity being stronger than potassium hydroxide. It is widely used in the condensation, rearrangement and ring opening reaction in organic production in the fields of chemical, pharmaceutical and pesticide.
Potassium tert-butoxide is a strong alkaline condensing agent with its alkalinity is stronger than sodium methoxide and sodium ethoxide. At room temperature, this product is white or white-like solid powder with its chemical formula being (CH3) 3C-O-K, molecular weight being 112.21, density being 0.929, the melting point of 256-258°C and the boiling point being 275°C. It is easy to absorb moisture. It is soluble in tert-butanol with the solution being relative stable, and commonly used in the dehydrohalogenation reaction of halogenated hydrocarbon. Being exposure to air decomposition, it can be decomposed into potassium oxide and tert-butyl alcohol when coming across water.
Application of Potassium tert-butoxide
Potassium tert-butoxide, as a strong alkaline, is widely used in the condensation, rearrangement and ring opening reaction in organic production in the fields of chemical, pharmaceutical and pesticide.
It can also be used:
To synthesize aliphatic and aromatic amides from corresponding esters and amines.
As a base in the intramolecular cyclization of aryl ethers, amines, and amides.
As a catalyst to prepare styrene derivatives from aryl halides and alkenes by Mizoroki-Heck reaction.
Potassium tert-butylate is used to catalyzes the Michael addition reaction.
| Potassium tert-butoxide Chemical Properties |
| Melting point | 256-258 °C (dec.) (lit.) |
| Boiling point | 275°C |
| density | 0.910 g/mL at 20 °C |
| bulk density | 500kg/m3 |
| vapor pressure | 1 mm Hg ( 220 °C) |
| Fp | 54 °F |
| storage temp. | Store below +30°C. |
| solubility | Soluble in hexane, toluene, diethyl ether and terahydrofuran. |
| form | Solution |
| pka | pK1:18(25°C) |
| color | White to off-white |
| Specific Gravity | 0.902 |
| PH | 13 (5g/l, H2O, 20℃)Hydrolysis |
| Water Solubility | REACTS |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| Sensitive | Moisture Sensitive |
| BRN | 3556712 |
| Stability: | Stable, but reacts violently with water and acids, possibly leading to fire. Incompatible with water, acids, halogenated hydrocarbons, alcohols, strong oxidizing agents, ketones, carbon dioxide. |
| InChI | 1S/C4H9O.K/c1-4(2,3)5;/h1-3H3;/q-1;+1 |
| InChIKey | LPNYRYFBWFDTMA-UHFFFAOYSA-N |
| SMILES | [K+].CC(C)(C)[O-] |
| CAS DataBase Reference | 865-47-4(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Methyl-2-propanol, potassium salt (865-47-4) |
| Safety Information |
| Hazard Codes | F,C,Xi |
| Risk Statements | 11-19-22-34-35-14-20-36/37-37 |
| Safety Statements | 16-26-36/37/39-43-45-7/9-8-43A-33-27-29 |
| RIDADR | UN 3274 3/PG 2 |
| WGK Germany | 1 |
| F | 10-21 |
| Autoignition Temperature | 483 °C |
| Hazard Note | Flammable solid/Corrosive |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | I |
| HS Code | 29051900 |
| Storage Class | 4.2 - Pyrophoric and self-heating hazardous materials |
| Hazard Classifications | Eye Dam. 1 Flam. Sol. 1 Self-heat. 2 Skin Corr. 1A |
Fact Factory and Equipment Show
