Tetrabutylammonium fluoride trihydrate #CAS87749-50-6
CAS Number:87749-50-6
Chemical Formula:C16H38FNO
Synonyms:
TETRA-N-BUTYLAMMONIUM FLUORIDE 3 H2O
Tetrabutylammoniumfluoridetrihydrate97%
Tetrabutylammonium fluoride trihydrate 97%
Appearance:White to off-white crystalline powder or lumps at ambient temperature, m.p.62~65℃; Extremely hygroscopic, rapidly deliquesces and even liquefies in air; Soluble in water, methanol, acetonitrile, THF and other polar organic solvents; The most commonly used silyl ether deprotecting agent in organic synthesis.
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Tetrabutylammonium fluoride trihydrate #CAS87749-50-6
Quaternary ammonium salt compound, fluorinating reagent, silyl ether deprotecting agent, organic synthesis base, phase transfer catalyst, pharmaceutical intermediate
UN1759, Class8 Corrosive Solid, Packing Group Ⅱ; GHS hazards: H314 Causes severe skin burns and eye damage, H302 Harmful if swallowed, H412 Harmful to aquatic life with long lasting effects
HS Code:2923900090, other quaternary ammonium salts and hydroxides
Tetrabutylammonium fluoride trihydrate is a commonly used salt within the realms of organic chemistry and biochemistry. This compound is employed as a potent base, finding extensive use in diverse applications, including organic compound synthesis, buffer preparation, and protein purification. It plays a pivotal role in the synthesis of various organic compounds, such as carboxylic acids, amines, and alcohols. Additionally, this compound facilitates the purification of nucleic acids, including DNA and RNA. Acting as a strong base, tetrabutylammonium fluoride trihydrate possesses the ability to deprotonate a wide range of organic compounds. It is commonly used in applications such as preparation of deprotecting agents, synthesis of lipophilic peprides during DNA transfections, and many more
Application of Tetrabutylammonium fluoride trihydrate
Reactant for:
Preparation of deprotecting agents in preparation of cellulose derivatives
Synthesis of lipophilic peptides for DNA transfections in vivo
Dehydrobromination reactions
| Tetrabutylammonium fluoride trihydrate Chemical Properties |
| Melting point | 62-63 °C(lit.) |
| Fp | -17℃ |
| storage temp. | Store below +30°C. |
| form | Crystalline Powder, Crystals and/or Chunks |
| Specific Gravity | 0.887 |
| color | White to slightly yellow |
| PH | pH (50g/l, 25℃) : 5.0～8.0 |
| Water Solubility | SOLUBLE |
| Sensitive | Hygroscopic |
| BRN | 3761900 |
| Exposure limits | ACGIH: TWA 2.5 mg/m3 NIOSH: IDLH 250 mg/m3 |
| InChI | InChI=1S/C16H36N.FH.H2O/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;;/h5-16H2,1-4H3;1H;1H2/q+1;;/p-1 |
| InChIKey | UQCWXKSHRQJGPH-UHFFFAOYSA-M |
| SMILES | [N+](CCCC)(CCCC)(CCCC)CCCC.[F-].O |
| CAS DataBase Reference | 87749-50-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | C,Xi |
| Risk Statements | 34-36/37/38 |
| Safety Statements | 26-36/37/39-45-26 37/39 |
| RIDADR | UN 1759 8/PG 1 |
| WGK Germany | 3 |
| F | 3-10 |
| Hazard Note | Irritant |
| TSCA | T |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 38220000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Aquatic Chronic 3 Eye Irrit. 2 Repr. 2 Skin Irrit. 2 |
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