Myricetin #CAS529-44-2

Myricetin #CAS529-44-2

Myricetin[529-44-2] is a flavonoid compound found in many fruits and vegetables, including red wine, that acts as a powerful antioxidant. Myricetin inhibits TBARS formation with an IC50 value of 6.34 and at 20 μM, blocks oxLDL uptake by U937-derived macrophages, reducing CD36 expression. Myricetin demonstrates potent chemopreventative potential by binding JAK1/STAT3 to inhibit the neoplastic transformation of murine JB6 P+ cells and inhibiting MEK1 kinase activity.

Myrica flavonoids have antioxidant properties. In vitro studies have shown that high concentrations of myrica flavonoids can lower LDL cholesterol. A Finnish study found that people with high myrica flavonoid intake had a lower incidence of prostate cancer. An eight-year study found that kaempferol, quercetin, and myrica flavonoids can reduce the risk of pancreatic cancer in smokers.

Application of Myricetin 

The FDA in USA has myricetin widely used in medicine, food, health care products and cosmetics. Foreign health products in American, health care medicine FYI has myricetin as additives which are treatment for the prevention of arthritis and various kinds of inflammation, especially for pregnancy and lactation is more suitable for women and babies. Myricetin with high purity has been widely used in food, medicine and cosmetic fields. As the further study for myricetin of the pharmacological effects, the demand of market of myricetin will increase sharply, The research and development prospect of myricetin are broad.
Myricetin is specialty resources in China. In view of the regional differences, the international on the research of myricetin is just started. In China now only the research of guangxi rattan tea containing myricetin study more, but zhejiang as big provinces is origin of myricetin. The research about the active ingredient for special local economic crops is one of the few. For myricetin, the research is relatively backward. In Ningbo, related companies have begun to development and application of myricetin in preliminary, striving for its industrialization. Liquid could be used in food additives, such as coarse extraction, separation and purifying of crude extract of active ingredients and pharmacological activity research, etc., and further accelerate the speed of traditional Chinese medicine (TCM) modernization in China.

Myricetin is used as an antioxidant. It is a cell-permeable flavonoid used in inflammatory, diabetes, and cancer studies. It is effective in protecting neurons against oxidative stresses. Further, it inhibits yeast alfa-glucosidase,1 glyoxalase I in vitro and bovine milk xanthine oxidase.

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