Hexamethylene Diisocyanate CAS：822-06-0
High Boiling Properties：This product generally has a boiling range between 255°C and 261°C, making it suitable for use in high-temperature industrial processes.
Controlled Water Reactivity：It shows low solubility in water and stable hydrolytic properties, allowing its use in specific water-based chemical systems.
Conditional Stability：Although stable under proper storage conditions, it must be kept away from moisture in the air to avoid unwanted chemical changes.
Industrial Applications：Thanks to its good heat resistance and specific reactivity, it is widely used in coatings, adhesives and sealants that require high-temperature performance.
Hexamethylene diisocyanate, commonly known as HDI, usually exists as a clear to light yellow liquid with a strong pungent odor. It has low solubility in water and will undergo slow hydrolysis when exposed to water-based environments. Its physical properties include a relative density of around 1.05 at room temperature, a melting range of -67°C to -55°C, and a boiling range of 255°C to 261°C. The saturated vapor density of this substance is 46 mg/m³ at 20°C and 137 mg/m³ at 30°C respectively.
Application of Hexamethylene diisocyanate
Hexamethylene diisocyanate (HDI) is one of the most common aliphatic disocyanates, It is a monomer used in the production of polyurethane foams and exceptionally high-quality coatings, and is found in some industrial paints and spray painting operations. It is a compound which reacts readily with water and alcohols (Von Burg 1993). It has a vapor pressure of 0.05 mm Hg at room temperature, but can be present in aerosol form allowing a potentially higher exposure to individuals. The HDI-BT trimer is often present for similar industrial uses. It would be expected to have a lower vapor pressure; however, the aerosol form can also be present, allowing potentially higher exposure of HDI-BT to individuals. Hexamethylene diisocyanate reacts slowly with water to form carbon dioxide (HSDB 1996). The base-catalyzed reaction of Hexamethylene diisocyanate with alcohols should be carried out in inert solvents; the reaction may occur with explosive violence in the absence of solvents (NFPA 1994).
1,6-Hexamethylenediisocyanate is a chemical intermediate used in the production of urethane products.
Parameters
| Melting point | -55°C |
| Boiling point | 82-85 °C/0.1 mmHg |
| density | 1.047 g/mL at 20 °C (lit.) 1.047 g/mL at 20 °C |
| vapor pressure | 0.05 mm Hg ( 25 °C) |
| refractive index | n20/D 1.453 |
| Fp | 248 °F |
| storage temp. | Store below +30°C. |
| form | Liquid |
| Specific Gravity | 1.05 |
| color | Clear colorless to slightly yellow |
| explosive limit | 0.9-9.5%(V) |
| Water Solubility | Reacts |
| Sensitive | Moisture Sensitive |
| BRN | 956709 |
| Exposure limits | TLV-TWA 0.0343 mg/m3 (0.005 ppm) (ACGIH). |
| Stability: | Stable. Moisture sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases, amines, acids. May react explosively with alcohols in the presence of base without a diluting solvent. Heating above 200 C may cause polymerization. |
| InChIKey | RRAMGCGOFNQTLD-UHFFFAOYSA-N |
| LogP | 3.2 at 20℃ |
| CAS DataBase Reference | 822-06-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,6-Hexamethylene diisocyanate(822-06-0) |
| EPA Substance Registry System | Hexamethylene-1,6-diisocyanate (822-06-0) |
Safety Information
| Hazard Codes | T,T+,F |
| Risk Statements | 23-36/37/38-42/43-41-34-26-22-39/23/24/25-23/24/25-11 |
| Safety Statements | 26-28-38-45-28A-36/37/39-23-36/37-16-7 |
| OEB | D |
| OEL | TWA: 0.005 ppm (0.035 mg/m3), Ceiling: 0.020 ppm (0.140 mg/m3) [10-minute] |
| RIDADR | UN 2281 6.1/PG 2 |
| WGK Germany | 1 |
| RTECS | MO1740000 |
| F | 10-19-21 |
| Autoignition Temperature | 454 °C |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | II |
| HS Code | 29291090 |
| Hazardous Substances Data | 822-06-0(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: 746 mg/kg LD50 dermal Rabbit 570 mg/kg |
