6-Hydroxy-1-naphthoic acid #CAS2437-17-4
CAS Number:2437-17-4
Chemical Formula:C11H8O3
Synonyms:
6-HYDROXY-1-NAPHTHOIC ACID
2-NAPHTHOL-5-CARBOXYLIC ACID
OHNA
Appearance:White to Brownpowder to Crystal
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
6-Hydroxy-1-naphthoic acid #CAS2437-17-4
6-Hydroxy-1-naphthoic acid is widely used as an organic synthesis intermediate and is an important raw material for pharmaceutical and dye production. In recent years, tyrosine kinase-targeting drugs (including monoclonal antibodies and small molecule compounds) have been actively developed and applied in various cancers, including hematologic malignancies, lung cancer, kidney cancer, colorectal cancer, gastric cancer, and liver cancer. Deritinib is a small molecule multi-target tyrosine kinase inhibitor targeting VEGFR1, VEGFR2, FGFR1, PDGFRβ, c-Kit, and c-Src; similar drugs have been successfully used in clinical anti-tumor treatment.
Application of 6-Hydroxy-1-naphthoic acid
6-Hydroxy-1-naphthoic acid can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical production processes.
| 6-Hydroxy-1-naphthoic acid Chemical Properties |
| Melting point | 210°C |
| Boiling point | 445.7±18.0 °C(Predicted) |
| density | 1.399±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 3.76±0.10(Predicted) |
| color | White to Brown |
| InChI | InChI=1S/C11H8O3/c12-8-4-5-9-7(6-8)2-1-3-10(9)11(13)14/h1-6,12H,(H,13,14) |
| InChIKey | JCJUKCIXTRWAQY-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=C2C(C=C(O)C=C2)=CC=C1 |
| CAS DataBase Reference | 2437-17-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-51-36-22 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29182900 |
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