• HPMC
  • HPMC

HPMC
English Name ：Hydroxypropyl Methyl Cellulose
English Synonyms ：HPMC; Hypromellose; Hydroxypropylmethylcellulose； Cellulose hydroxypropyl methyl ether; [Additional pharmaceutical-grade aliases]
CAS Number ：9004-65-3
Molecular Formula ：(C₆H₇O₂(OH)ₓ(OCH₃)ᵧ(OCH₂CH(OH)CH₃)₂)ₙ (Polymeric - C₁₂H₂₀O₁₀ is incorrect) **
Molecular Weight ：~10,000–1,500,000 g/mol (Variable by grade) • 324.28 is invalid **
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English NameHydroxypropyl Methyl Cellulose
English Synonyms

HPMC; Hypromellose; Hydroxypropylmethylcellulose;

Cellulose hydroxypropyl methyl ether; [Additional pharmaceutical-grade aliases]

CAS Number9004-65-3
Molecular Formula(C₆H₇O₂(OH)ₓ(OCH₃)ᵧ(OCH₂CH(OH)CH₃)₂)ₙ (Polymeric - C₁₂H₂₀O₁₀ is incorrect) **
Molecular Weight~10,000–1,500,000 g/mol (Variable by grade) • 324.28 is invalid **
InChINot applicable for polymers • Provided InChI describes a specific oligomer
Molecular Structure

1753255479806545698485002240


Density1.39 g/cm³ (Bulk density)
Melting PointDecomposes at ~200°C (Not 1.39 - value likely erroneous) **
Boiling PointN/A (Decomposes before boiling) • 1101.5°C invalid **
Flash Point>250°C (Non-flammable) • 619.9°C invalid **
Water SolubilitySoluble (forms colloidal solutions)
Vapor Pressure0 mmHg at 25°C
Physicochemical Properties• Appearance: White to off-white powder
• Gelation Temp: 50-90°C (grade-dependent)
• Viscosity: 5-100,000 mPa·s (2% solution)
Applications• Pharmaceuticals: Tablet binder/coating agent
• Food Industry: Thickener/stabilizer (E464)
• Construction: Cement additive
• Coatings: Film former
• Resins: Dispersion stabilizer
Safety PhrasesS24/25: Avoid skin and eye contact
Upstream Raw MaterialsCellulose (cotton linter/wood pulp), Propylene Oxide, Methyl Chloride, Sodium Hydroxide, Hydrochloric Acid
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